Abstract— Lutein ester was extracted from marigold petals under hexane reflux at 60°C. For protection from oxidation, the as-obtained lutein ester was clathrated with β-cyclodextrin (β-CD) using two methods, viz. grinding lutein ester with β-CD in the presence of ethanol and through the mixing of an ethanol solution of lutein ester with an aqueous solution of β-CD. The results of DSC, IR, H1NMR analyses suggest successful clathration of lutein ester in β-CD. In terms of inclusion efficiency, the former is better than the latter to achieve clathration. We studied factors that can affect the stability of lutein ester such as light, air and temperature change, and the results confirm good stability of the clathrated lutein ester. The toxicity and pharmacokinetic tests on mice showed that the lutein-β-cyclodextrin complex is non-toxic and has an efficient release rate that matches body physiology.
Keywords— Lutein ester; Marigold petals; β-Cyclodextrin; Clathrated compound; Toxicity test.
Click here to Download Full Paper
AD Publications is a rapidly growing academic publisher in the fields of Engineering, Medical-Health, Environmental Science and Agriculture Research. AD Publications is a registered organization broad-based open access and publishes most exciting researches with respect to the subjects of our journals. The Journals is being indexed and abstracted by all major global current awareness and alerting services.
The organization aims at undertaking, co- coordinating and promoting research and development. It provides professional and academic guidance in the field of basic education, Higher Education as well in the Technical Education. Our Aims is to Promote and support, High Quality basic, Scientific Research and development in fields of Engineering, Medical-Health, Environmental Science and Agriculture Research and to Generate Public awareness, provide advice to scholar’s researchers and communicate research outcomes.
Some Important Links About Research Journal
International Journal
Agriculture Journal
Medical Journal
Environmental Journal
Engineering Journal